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Spectra Staff

BTMPS Added to the Amplifi ID Detection Library

Updated: Dec 17

Bis(2,2,6,6-tetramethyl-4-piperidyl) sebacate (abbreviated as BTMPS) is an industrial-grade compound used in plastic manufacturing. It was not designed or approved for human or animal consumption. The compound is corrosive and has known negative health risks listed on the safety data sheets from its suppliers. Our team has just added BTMPS to Amplifi IDs Bulk Scan library in response to its recent emergence across the US drug supply.

 

Our team tested and collected spectra of both the "free base" and hydrochloride salt versions of the substance. The hydrochloride salt is what is reported to show up in the drug supply, as its soluble in water whereas the free base is not.


Comparison of the Raman spectra of BTMPS "Free base" and BTMPS-HCl
Comparison of the Raman spectra of BTMPS "Free base" and BTMPS-HCl

BTMPS can be readily acquired from chemical manufacturers given that it is not a controlled substance. When our team was working with this compound in the lab, one observation we made was that its density was noticeably lower than other common cuts found in drug samples, such as sugar and caffeine, which could explain its possible use as a bulking agent. However, the reasons for it being found in the drug supply are still unknown. The UNC Street Drug Analysis Lab from the University of North Carolina at Chapel Hill has a comprehensive post on BTMPS’s properties, emergence, and theories as to why it has made its way into the drug supply this year. Most experts agree that this compound should be avoided given its adverse health impacts.


Visual comparison of BTMPS and two common cutting agents Mannitol and Caffeine
Visual comparison of BTMPS and two common cutting agents Mannitol and Caffeine

Substance

Density

BTMPS

1.05 g/cm^3

D-Mannitol

1.49 g/cm^3

Caffeine

1.23 g/cm^3

Contact Us

Our team is committed to rapidly responding to the changing landscape to ensure frontline teams and scientists are equipped to address new drug checking challenges. If you are a current Amplifi ID user with a substance you'd like to see added, or someone interested in learning more about what Amplifi ID can detect, please feel free to get in touch.

 

Acknowledgements

We thank our collaborators, Dr. Carlos Escobedo and Dr. Hridaynath Bhattacharjee from Queen’s University, Kingston, ON, for the support and knowledge provided.

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