ID-100 Ag SERS Substrate



Our enhancement across analytes is significantly greater than popular competitors on the market.

Repeatable SERS signal

Our SERS substrates are double-checked for quality before shipping, ensuring that your substrates produce high quality SERS signals for the analytes in question.


Our substrate surfaces can be modified with a variety of molecules to improve specificity for certain analytes. We can also modify the shape of the SERS active area or the form factors  surrounding it.


Achieve ultra-high sensitivity without an ultra-high price tag.

Technical Specifications

Spectra Plasmonics SERS Ag Substrate Specifications

The Process

Add Sample

Fast Chemical Detection SERS substrate

Drop-cast analyte, or submerge the substrate in analyte solution and allow the solvent to evaporate.


Raman Spectrometer SERS

Fire the excitation laser from your Raman system to excite your sample.


Chemical Detection SERS substrate

Analyze the enhanced spectral information on your spectrometer’s software.

Application Examples


Melamine is an organic base chemical widely used in plastics and adhesives. It is notoriously known for being a harmful food adulterant as it can boost food’s apparent protein content. In 2007, melamine was added to pet food sold in the United States which killed hundreds of domestic house pets. In 2008, the chemical was added to infant formula in China, leading to over 50,000 hospitalizations and several infant deaths.

The World Health Organization sets a safe allowable concentration for melamine in milk at 2.5 ppm and in infant formula at 1 ppm.

Spectra Plasmonics Ag-SERS substrates can detect melamine confidently at 1 ppm with greater sensitivity than our competitors. We have also demonstrated detection of melamine at 1 ppm in milk after a simple extraction process.

Melamine SERS spectra


Thiram is commonly used as a fungicide, ectoparasiticide and animal repellant in industry and agriculture. Thiram is toxic upon ingestion — it is a skin and mucous membrane irritant, hepatotoxic, neurotoxic, and teratogenic. The US Environmental Protection Agency dictates 7 ppm as the maximal residue limit (MRL) for thiram in food products.

Spectra Plasmonics Ag-SERS substrates can reproducibility detect thiram at ppb levels. We have also demonstrated trace detection in apple juice with no sample preparation.

For application inquiries for other pesticides, please contact us.

Thiram SERS detection


SERS can aid in the Raman analysis of narcotic samples in two ways:

  • Increasing the Raman signal in samples that are masked by high amounts of fluorescence.
  • Detecting trace amounts of cutting agents or other substances in the seized material.

Spectra Plasmonics SERS substrates can detect the following compounds in dilute amounts:

  • Cocaine
  • Methamphetamine
  • Heroine
  • Oxycodone
Cocaine detection SERS